Western blot analysis of extracts of various cell lines, using KLRC1 antibody (A1233) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 5min.
KLRC1 Rabbit pAb
Catalog No:AB-A1233
Manufacturer:ABclonal
Synonyms:KLRC1;CD159A;NKG2;NKG2A
Applications:WB
Reactivity:Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | KLRC1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 96-215 of human KLRC1 (NP_015567.1). |
Gene ID: | 3821 |
Swiss prot: | P26715 |
Molecular weight: | 24kDa/26kDa |
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