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Western blot analysis of extracts of various cell lines, using AKR7A2 antibody (A1227) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).
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Immunohistochemistry of paraffin-embedded mouse heart using AKR7A2 antibody (A1227) at dilution of 1:100 (40x lens).
AKR7A2 Rabbit pAb
Catalog No：AB-A1227
Manufacturer：ABclonal
Synonyms：AKR7A2;AFAR;AFAR1;AFB1-AR1;AKR7
Applications：WB,IHC,IF
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | AKR7A2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-359 of human AKR7A2 (NP_003680.2). |
| Gene ID: | 8574 |
| Swiss prot: | O43488 |
| Molecular weight: | 39kDa |
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