Fosaprepitant dimeglumine [Cas No. 265121-04-8]
Catalog No:TA-T1790
Manufacturer:TargetMol
Synonyms:L785298,MK-0517,Fosaprepitant dimeglumine salt
CAS No.:265121-04-8
Formula:C37H56F7N6O16P
MWt:1004.83
€54,00 – €409,00
Name: | Fosaprepitant dimeglumine |
Category: | Biochemicals |
Description: | Fosaprepitant Dimeglumine is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent binds selectively to the human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS). This inhibits receptor binding of the endogenous substance P and prevents substance P-induced emesis. |
Pathway: | Neuroscience |
Target: | Neurokinin Receptor antagonist |
Receptor: | NK1 |
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