NU6140 [Cas No. 444723-13-1]
Catalog No：TA-T16359
Manufacturer：TargetMol
CAS No.：444723-13-1
Formula：C23H30N6O2
MWt：422.52
€111,00 – €1.818,00
| Name: | NU6140 |
| Category: | Biochemicals |
| Description: | NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM). It shows 10- to 36-fold selectivity over other CDKs. NU6140 also effectively inhibits Aurora A and Aurora B (IC50s: 67 and 35 nM, respectively). It also enhances the apoptotic effect and has anti-cancer activity. |
| Pathway: | Cell Cycle/Checkpoint,Chromatin/Epigenetic |
| Target: | Aurora Kinase,CDK |
| Receptor: | Aurora A,Aurora B,CDK1/CyclinB,cdk2/cyclinA,CDK4/CyclinD,cdk5/p25,cdk7/cyclinH |
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