Naftifine hydrochloride [Cas No. 65473-14-5]
Catalog No:TA-T1543
Manufacturer:TargetMol
Synonyms:Naftifine HCl,Naftin,Exoderil,Naftifungin
CAS No.:65473-14-5
Formula:C21H22ClN
MWt:323.86
€30,00
Name: | Naftifine hydrochloride |
Category: | Biochemicals |
Description: | Naftifine Hydrochloride is the hydrochloride salt form of naftifine, an allylamine derivate with synthetic broad-spectrum antifungal activity. Although the exact mechanism through which naftifine hydrochloride exerts its effect is unknown, it appears to selectively inhibit the enzyme squalene 2, 3-epoxidase, thereby inhibiting the biosynthesis of sterol. This results in a decreased amount of sterols, especially ergosterol which is the primary fungal membrane sterol, and a corresponding accumulation of squalene in fungal cells. Naftifine hydrochloride can be fungicidal as well as fungistatic to yeasts depending on the concentration and the organisms involved. |
Pathway: | GPCR/G Protein, Stem Cells |
Target: | Hedgehog/Smoothened agonist |
Receptor: | Smoothened |
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