E 2012 [Cas No. 870843-42-8]
Catalog No:TA-T15184
Manufacturer:TargetMol
CAS No.:870843-42-8
Formula:C25H26FN3O2
MWt:419.49
€79,00 – €1.282,00
Name: | E 2012 |
Category: | Biochemicals |
Description: | E2012 is a γ-secretase modulator (GSM). E2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer’s disease by reduction of amyloid β-42, and induces cataract following repeated doses in the rat. |
Pathway: | Neuroscience, Proteases & Proteasome, Stem Cells |
Target: | Gamma-secretase |
Receptor: | γ secretase |
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