CU-T12-9 [Cas No. 1821387-73-8]
Catalog No：TA-T15017
Manufacturer：TargetMol
CAS No.：1821387-73-8
Formula：C17H13F3N4O2
MWt：362.31
€78,00 – €801,00
| Name: | CU-T12-9 |
| Category: | Biochemicals |
| Description: | CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and iNOS. |
| Pathway: | Immunology & Inflammation |
| Target: | TLR |
| Receptor: | TLR2,TLR1 |
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