Western blot analysis of extracts of various cell lines, using LILRB2 antibody (A12157) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
LILRB2 Rabbit pAb
Catalog No:AB-A12157
Manufacturer:ABclonal
Synonyms:LILRB2;CD85D;ILT-4;ILT4;LIR-2;LIR2;MIR-10;MIR10
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | LILRB2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 479-598 of human LILRB2 (NP_005865.3). |
Gene ID: | 10288 |
Swiss prot: | Q8N423 |
Molecular weight: | 51kDa/55kDa/64kDa/65kDa |
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