(S,R,S)-AHPC-Me hydrochloride [Cas No. 1948273-03-7]
Catalog No：TA-T13671
Manufacturer：TargetMol
Synonyms：VHL ligand 2 hydrochloride,E3 ligase Ligand 1
CAS No.：1948273-03-7
Formula：C23H33ClN4O3S
MWt：481.05
€247,00 – €735,00
| Name: | (S,R,S)-AHPC-Me hydrochloride |
| Category: | Biochemicals |
| Description: | (S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM. (S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. |
| Pathway: | PROTAC |
| Target: | Ligand for E3 Ligase |
| Receptor: | VHL |
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