Rofecoxib [Cas No. 162011-90-7]
Catalog No:TA-T1185
Manufacturer:TargetMol
Synonyms:MK 966,MK-0966
CAS No.:162011-90-7
Formula:C17H14O4S
MWt:314.36
€38,00 – €69,00
Name: | Rofecoxib |
Category: | Biochemicals |
Description: | Rofecoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of phenyl-furanone with anti-inflammatory, antipyretic and analgesic properties and potential antineoplastic properties. COX-related metabolic pathways may represent key regulators of cell proliferation and neo-angiogenesis. Some epithelial tumor cell types overexpress pro-angiogenic COX-2. |
Pathway: | Immunology & Inflammation, Neuroscience |
Target: | COX inhibitor |
Receptor: | COX-2 |
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