APX-115 free base [Cas No. 1270084-92-8]
Catalog No：TA-T10353
Manufacturer：TargetMol
Synonyms：Ewha-18278 free base
CAS No.：1270084-92-8
Formula：C17H17N3O
MWt：279.34
€51,00 – €1.216,00
| Name: | APX-115 free base |
| Category: | Biochemicals |
| Description: | APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase （Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kidney injury. |
| Pathway: | Immunology & Inflammation |
| Target: | NADPH-oxidase |
| Receptor: | Nox1,Nox2,Nox4 |
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