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Western blot analysis of extracts of various cell lines, using TAK1 antibody (A12022) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
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Immunohistochemistry of paraffin-embedded rat kidney using TAK1 Rabbit pAb (A12022) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse testis using TAK1 Rabbit pAb (A12022) at dilution of 1:100 (40x lens).
TAK1 Rabbit pAb
Catalog No：AB-A12022
Manufacturer：ABclonal
Synonyms：CSCF;FMD2;MEKK7;TAK1;TGF1a;MAP3K7
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | TAK1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-470 of human TAK1 (NP_003179.1). |
| Gene ID: | 6885 |
| Swiss prot: | O43318 |
| Molecular weight: | 53kDa/56kDa/64kDa/67kDa |
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