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Western blot analysis of extracts of various cell lines, using Ser/thr-PP2A activator (PTPA) antibody (A11999) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 20s.
Ser/thr-PP2A activator (PTPA) Rabbit pAb
Catalog No：AB-A11999
Manufacturer：ABclonal
Synonyms：PTPA;PP2A;PPP2R4;PR53
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | Ser/thr-PP2A activator (PTPA) Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B’/PR61, and B”/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B’ family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 52-230 of human Ser/thr-PP2A activator (PTPA) (NP_821067.1). |
| Gene ID: | 5524 |
| Swiss prot: | Q15257 |
| Molecular weight: | 31kDa/33kDa/36kDa/40kDa |
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