Clozapine [Cas No. 5786-21-0]
Catalog No：TA-T0455
Manufacturer：TargetMol
Synonyms：HF 1854,LX 100-129
CAS No.：5786-21-0
Formula：C18H19ClN4
MWt：326.82
€50,00 – €140,00
| Name: | Clozapine |
| Category: | Biochemicals |
| Description: | Clozapine is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. |
| Pathway: | GPCR/G Protein, Neuroscience |
| Target: | AChR antagonist, Adrenergic Receptor agonist, Dopamine Receptor antagonist |
| Receptor: | M1 mAChR, α2-adrenoceptor, D2 |
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