Western blot analysis of extracts of HeLa cells, using Thyroglobulin antibody (A11708) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s.
Thyroglobulin Rabbit pAb
Catalog No:AB-A11708
Manufacturer:ABclonal
Synonyms:TG;AITD3;TGN
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | Thyroglobulin Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2469-2768 of human Thyroglobulin (NP_003226.4). |
Gene ID: | 7038 |
Swiss prot: | P01266 |
Molecular weight: | 298kDa/304kDa |
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